abstract |
A fused [1,2] imidazo [4,5-c] cyclic compound having a —CH (—X 1 —R 1 ) — group in the fused ring at the 1-position of the imidazo ring (for example, imidazo [4,5-c Quinoline, 6,7,8,9-tetrahydroimidazo [4,5-c] quinoline, imidazo [4,5-c] naphthyridine, and 6,7,8,9-tetrahydroimidazo [4,5-c] Naphthyridine), pharmaceutical compositions containing the compounds, intermediates, methods for producing the compounds, and immunization of these compounds for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases A method of use as a modulator is disclosed. |