abstract |
Formula (I) [wherein, for example R 1 is aryl or heteroaryl is optionally substituted; Y is, for example, a linking group selected from a direct bond and (substituted) alkyl chain; R 2 is Are optionally substituted aryl, optionally substituted cycloalkyl, or optionally substituted heterocyclic group, and salts and prodrugs thereof. Also described are methods of making such compounds and their use as DGAT inhibitors, for example in the treatment of obesity. |