abstract |
The present invention relates to general formula (I) Disclosed is a fused thienopyridyl compound wherein X 1 -X 6 , R 5 -R 7 , Z 1 and L are as defined herein. Or the present invention uses these compounds to inhibit VR1 receptors in mammals, methods to control pain, urinary incontinence, bladder overactivity and inflammatory thermal hyperalgesia in mammals, and these compounds A pharmaceutical composition comprising is also disclosed. |