| abstract |
[Chemical 1] The present invention is a novel replacement having binding affinity for serotonin receptors, particularly 5-HT 2A and 5-HT 2C receptors, and for dopamine receptors, particularly dopamine D2 receptors, and having norepinephrine reuptake inhibitory properties. And tetracyclic tetrahydrofuran, pyrrolidine and tetrahydrothiophene derivatives, pharmaceutical compositions comprising the compounds of the invention, in particular for preventing a series of mental and neurological disorders, in particular certain mental, cardiovascular and gastric motility disorders and / or Or, for treatment, its use as a medicament, as well as methods for their production. The compounds of the invention can be represented by the general formula (I) and also include their pharmaceutically acceptable acid or base addition salts, their stereochemical isomers, their N-oxide forms and their prodrugs. Where all substituents are as defined in claim 1. |