http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008523027-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
filingDate | 2005-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2008-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2008523027-A |
titleOfInvention | Tetrahydropyridin-4-ylindoles with a combination of affinity for the dopamine-D2 receptor and a serotonin resorption site |
abstract | [Chemical 1] The present invention is a group of novel tetrahydropyridin-4-yl indoles having an affinity about serotonin reuptake inhibitory and dopamine -D 2 receptor is a dual activity system, manufacturing method, and the tetrahydropyridine of these compounds -4 -It relates to a novel intermediate useful for the synthesis of ylindoles. The invention also relates to the use of the compounds disclosed herein for the manufacture of medicaments that provide advantageous effects. The present invention relates to novel tetrahydropyridin-4-ylindoles of formula (I) and their tautomers, stereoisomers, prodrugs, N-oxides, pharmaceutically acceptable salts, hydrates and relates solvates, where -R 1 is hydrogen, halogen, alkyl (C 1-3) or alkoxy (C 1-3), CN or CF 3, -R 2 is hydrogen or alkyl (C 1-3 ), and, -R 3 is hydrogen or alkyl (C 1-3), -Z is hydrogen or alkyl (C 1-3), alkoxy (C 1-3) or alkylthio (C 1-3) , -A is hydrogen or alkyl (C 1-3 ), or -A and Z together are saturated or (partially) optionally substituted by halogen, alkyl (C 1-3 ) or phenyl Unsaturated A 5- or 6-membered ring, wherein ring Z represents carbon, sulfur or nitrogen. |
priorityDate | 2004-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.