| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10362
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10352
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-075 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2005-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2008-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2008522630-A |
| titleOfInvention |
Cell lines for the production of replication-deficient adenoviruses. |
| abstract |
The present invention provides cell lines for the production of E1-deficient adenovirus (rAd) vectors that complement the functions of E1A and E1B. The invention also provides cell lines for the production of E1-deficient and E2-deficient adenoviral vectors that complement the polymerase function of E1A, E1B and E2B. The present invention provides specific cell lines that supplement E1A function by insertion of E1A sequences containing mutations in the 243R and 289R proteins, and E1B sequences containing the E1B-55K gene. The production yield in the resulting production cell lines (named SL0003 and SL0006) is similar to the production yield obtained from 293 cells without producing a recombinant adenovirus ("RCA") with detectable replication ability. Was. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190067131-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7319368-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102173189-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11746334-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180118560-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299713-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015500007-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102122117-B1 |
| priorityDate |
2004-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |