abstract |
The present invention is an inhibitor of dipeptidyl peptidase-IV enzyme ("DPP-IV inhibitor"), in the treatment or prevention of diseases involving dipeptidyl peptidase-IV enzyme, such as diabetes and especially type 2 diabetes. It is directed to novel substituted fused aminopiperidines that are useful. The present invention is also directed to pharmaceutical compositions comprising these compounds, and the use of these compounds and compositions in the prevention or treatment of diseases involving the dipeptidyl peptidase-IV enzyme. [Chemical 1] |