| abstract |
Method and system for delivering pharmacological agents, particularly NO donors, to the heart via the vascular system and atrial wall, in particular through the superior vena cava and right atrial wall, transvenously into the pericardial space Is disclosed. The proximal connector of the infusion catheter is coupled to the infusion pump, and a distal catheter segment having a distal infusion catheter lumen end opening is disposed in the pericardial space. The implantable infusion pump is operable with an implantable ischemia monitor that monitors ischemic conditions and triggers the delivery of a pharmacological agent or schedules the pharmacological agent to optimally treat ischemia. Adjust the typical delivery. When the patient feels ischemic, the patient activator can be operated to send a signal received by the implantable infusion pump to trigger delivery of the bolus and / or continuous infusion. |