abstract |
[Chemical 1] VIII The present invention relates to a compound of the formula I [wherein M is a macrolide subunit represented by the partial structure VIII: L is a chain represented by the partial structure IX or XIII: Z is a steroid having anti-inflammatory activity. Alternatively, it is a steroid or non-steroid subunit derived from a non-steroidal drug (NSAID). ] It is related with the new compound represented by this. The present invention also provides improved pharmaceutically acceptable salts and solvates of such prepared compounds, methods and intermediates for their preparation, and treatment of inflammatory diseases and conditions in humans and animals. It relates to therapeutic action and use. |