http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008517893-A
Outgoing Links
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
filingDate | 2005-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2008-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2008517893-A |
titleOfInvention | Pharmaceutical compounds |
abstract | Embedded image [Wherein A represents a thiophene or furan ring; n is 1 or 2; R 1 is formula (1); [wherein m is 0 or 1; R 30 is H Or C 1 -C 6 alkyl; R 4 and R 5 , together with the N atom to which they are attached, may be fused to a benzene ring and are unsubstituted or substituted, N, S, Or a 5- or 6-membered saturated N-containing heterocyclic group containing 0 or 1 additional heteroatom selected from and O; or one of R 4 and R 5 is alkyl And the other is a 5- or 6-membered saturated N-containing heterocyclic group as defined above or an alkyl group substituted by a 5- or 6-membered saturated N-containing heterocyclic group as defined above] R2 is a group represented by formula (a); wherein R 6 and R 7 are a bond Forming an unsubstituted or substituted morpholine, thiomorpholine, piperidine, piperazine, oxazepane, or thiazepane group with the nitrogen atom in which they are formed]; and formula (b); [wherein Y is a chain C 1 — containing 1 or 2 heteroatoms selected from O, N, and S between constituent carbon atoms and / or at one or both ends of the chain, and being unsubstituted or substituted C 4 is an alkylene chain]; and fused pyrimidine of R 3 is an indole group which is unsubstituted or substituted]; and pharmaceutically acceptable salts thereof, activity as inhibitors of PI3 kinase Thus, abnormal cell proliferation, function associated with PI3 kinase, such as cancer, immune disorders, cardiovascular diseases, viral infections, inflammation, metabolic / endocrine disorders, and neurological disorders Or can be used to treat diseases and disorders resulting from behavior. A method of synthesizing the compound is also described. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009534453-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011500775-A |
priorityDate | 2004-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 481.