| abstract |
The present invention relates to an anti-hemolytic binding member comprising at least one binding domain capable of specifically binding to pneumolysin, in particular a binding member having at least two binding domains, in diagnostic methods, and for treatment Regarding the use of binding members. In a preferred embodiment, the binding member is an antibody, such as a human antibody, or a fragment thereof, which may be a bispecific antibody. This binding domain has a dissociation constant K d for pneumolysin that is less than 1 × 10 −6 . Preferably, the binding member comprising the binding domain has a dissociation constant K d as defined above. |