abstract |
Compositions and methods for formulating and delivering adjuvanted immunoactive agents, particularly vaccines, that alleviate or avoid adjuvant coagulation and the concomitant loss of vaccine efficacy. Adjuvant immunoactive agents can be subjected to freezing, drying, lyophilization, or lyophilization, and retain high levels of effectiveness when reduced. The present invention further provides compositions and methods for formulating and delivering stable adjuvant immunoactive agents that can be deposited on transdermal delivery devices or microprojections or arrays thereof. |