| abstract |
Formula 1: [Wherein the symbols are as defined in the description] Is a α 2 adrenergic receptor agonist. Some of the compounds of the present invention are specific or selective for α 2B and / or α 2C adrenergic receptors over α 2A adrenergic receptors. In addition, some of the compounds of the invention have no or minimal cardiovascular and / or sedative effects. The compounds of formula 1 are useful as therapeutic agents for mammals, including humans, for the treatment of diseases and / or relief of symptoms in response to treatment with α 2 adrenergic receptor agonists. Compounds of formula 1 that do not have significant cardiovascular and / or sedative effects are useful for treating pain and other conditions with minimal side effects. |