abstract |
The present invention relates to 8-fluoro-2 {4-[(methylamino) methyl] phenyl} -1,3,4 represented by formula (1) as a chemical sensitizer that increases cytotoxicity or radiotherapy. , 5-Tetrahydro-6H-azepino [5,4,3-cd] indol-6-one. The present invention relates to 8-fluoro-2- {4-[(methylamino) methyl] phenyl} -1,3,4,5-tetrahydro-6H-azepino [5,4,3-cd] indol-6-one. Or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition of at least one additional therapeutic agent, a kit containing such a combination, and such for treating a patient suffering from a disease such as cancer A method using various combinations is provided. |