http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008513368-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 |
| filingDate | 2005-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2008513368-A |
| titleOfInvention | Process for preparing substituted 8-azabicyclo [3.2.1] octan-3-ols |
| abstract | The present invention relates to a process for preparing a substituted 8-azabicyclo [3.2.1] octan-3-ol having the structural formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein R is benzyl, R 5 -benzyl, allyl, —C (O) R 6 , —C (O) OR 8 or —CH (R 7 ) 2 ; R 1 is optionally substituted aryl or Optionally substituted heteroaryl; and R 5 , R 6 , R 7 and R 8 are as defined herein; the method comprises: a) an amine R—NH of formula (II) 2 II and 2,5-dimethoxytetrahydrofuran or HC (O) (CH 2 ) 2 C (O) H, and C (O) (CH 2 C (O) OR 4 ) 2 (where R 4 is H or alkyl) to give a compound of formula II A step of obtaining a compound of formula I, b) a step of reacting a compound of formula (III) with I—R 1 , an alkyl lithium, and optionally a lithium salt to obtain a compound of formula I. |
| priorityDate | 2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.