abstract |
The present invention relates to the fields of medicine, immunology, virology and molecular biology. The present invention provides a composition comprising modified virus-like particles (VLPs) derived from RNA bacteriophage AP205. The present invention also provides a method for producing the aforementioned VLP. The modified virus-like particles disclosed in the present invention are useful for the production of compositions for eliciting an immune response for the prevention or treatment of diseases, disorders including infectious diseases, allergies, cancer and drug addiction. . Furthermore, the modified virus-like particles of the present invention are particularly useful for effectively inducing a self-specific immune response, particularly an antibody response. |