abstract |
Many diseases are associated with the production of effector cells. The present invention relates to the recognition that effector cells undergo cyclic changes in these diseases. Furthermore, the present invention relates to the measurement of regulator cells undergoing cyclic changes in degenerative diseases. Based on these recognitions, the present invention provides methods for treating conditions such as autoimmune diseases, degenerative diseases, and graft-versus-host disease. The present invention also relates to a method for determining when a therapeutic agent should be administered to a patient. |