abstract |
The present invention comprises an implantable structural element for delivery of a bioactive agent to a body site that is controlled in vivo. The implantable structural element can be configured as an implantable prosthesis, such as an endoluminal stent, heart valve, bone implant, etc., and exhibits the dual function of being a prosthesis and also a carrier for bioactive agents To do. The elution of the bioactive agent is controlled by a plurality of cantilevered cover members, and the drug is not eluted until the cover member is opened by the intrinsic and extrinsic stimuli to elute the drug. |