abstract |
The present invention includes a novel compound represented by the following general formula (formula I), wherein R is a linear or cyclic alkyl group, and X is oxygen or sulfur, or It is an imino group or is not present, R ′ is an amino group or a methoxy group, or a fluorine atom or a chlorine atom, and n is 0, 1 or 2. These compounds are useful for binding to the tail or Fc portion of an immunoglobulin, and are therefore useful in applications where a specific molecule is required to interact non-covalently with the Fc portion of an immunoglobulin. It has sex. Such uses include the detection and purification of immunoglobulins and the treatment of certain autoimmune diseases. |