| abstract |
PROBLEM TO BE SOLVED: To provide a 2-sulfanyl-benzimidazol-1-yl-acetic acid derivative and a “chemotactic substance receptor homologous molecule expressed in Th2 cells” antagonist which is powerful for the treatment of prostalazine-mediated diseases. To their use as pharmaceutical compositions, pharmaceutical compositions containing these derivatives, and the preparation of these derivatives. Such derivatives treat diseases that respond to blockade of the interaction between CRTH2 receptor and PGD 2 , especially allergic asthma, rhinitis, chronic obstructive pulmonary disease (COPD), dermatitis, inflammatory bowel disease, rheumatoid arthritis Related to process or method. [Selection figure] None |