| abstract |
The present invention encompasses methods for the treatment and prevention of diseases, postoperative disorders and bacterial infections associated with lactosylceramide. The methods of the present invention generally employ LacCer synthase, (GalT-V / VI), PECAM-1, to treat a subject suffering from or likely to suffer from symptoms caused by VEGF. It is provided that one or more compounds that alter the activity of a VEGF pathway member, including VEGFR, VEGF or related pathway member, are administered to a subject. The present invention also provides methods for detecting and analyzing compounds that have the ability to treat such symptoms. [Selection] Figure 1-1 |