abstract |
The present invention comprises at least two layers, at least one active ingredient having high pH-dependent solubility, at least one pharmaceutically acceptable pH maintenance excipient and at least one pharmaceutically acceptable matrix-forming excipient. A controlled-release multi-layer tablet, wherein the at least one active ingredient having high pH-dependent solubility and the at least one pharmaceutically acceptable pH maintenance excipient are each contained in at least one different layer The present invention relates to a controlled drug release multilayer tablet. |