abstract |
A highly selective melanocortin-4 receptor antagonist wherein R 1 , R 2 , R 3 , R 4a , R 4b , R 5 , R 6 , R 7 , x, y, and z are defined in the specification And a method of treating weight disorders including cachexia, sarcopenia, and wasting syndrome or wasting disease, and a method of treating inflammation and immune disorders. |