| abstract |
The present invention provides a novel method and material for producing an optically active β-amino acid that binds to the alpha-2-delta (α2δ) subunit of a calcium channel. Equation 1 [Chemical 1] A process for preparing a compound of: Formula 2 [Chemical 2] Or Equation 4 [Chemical Formula 3] Is reacted with H 2 in the presence of a chiral catalyst to give a compound of formula 3 [Formula 4] And optionally converting a compound of formula 3 to a compound of formula 1; Comprising a method. [Selection figure] None |