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filingDate 2005-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2008-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2008505160-A
titleOfInvention Solid form of magnesium salt of (S) -omeprazole and method for producing the same
abstract a) Crystallizing S-omeprazole magnesium salt from a solution of S-omeprazole magnesium salt in a solvent system containing a methanol / water mixture with an amount of water of 0.01 ml or more per gram of S-omeprazole magnesium salt starting material B) separating the S-omeprazole magnesium salt appearing in the previous step; c) separating the free organic solvent from the obtained S-omeprazole magnesium salt, or separating both the free solvent and the solvating solvent; A new solid form of the active ingredient magnesium salt of S-omeprazole obtainable by a production process comprising: This new solid form is obtained by a reliable method with high yield and high optical purity that is useful for the production of pharmaceuticals containing the active ingredient.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010540413-A
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