| abstract |
The composition comprises particles comprising at least about 95% by weight of amphotericin B, wherein the particles have a mass median diameter of about 1.1 μm to about 1.9 μm. Other compositions also include particles comprising at least about 95% by weight of amphotericin B, wherein at least about 80% by weight of the particles have a geometric particle size of from about 1.1 μm to about 1.9 μm. Yet another composition comprises particles comprising amphotericin B, the particles having a mass median diameter of less than about 1.9 μm, and the amphotericin B having a crystallinity of at least about 20%. Unit dosage forms, delivery systems, and methods can include similar compositions. |