Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-785 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-765 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-329 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-00 |
filingDate |
2005-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2008-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2008502788-A |
titleOfInvention |
Preparation of polymer conjugates by four-component condensation reaction |
abstract |
Polymer-biomolecule conjugates are generally prepared in a site-specific or site-selective manner by a four-component condensation reaction. This method can be used to prepare conjugates in which two polymer molecules are attached to a single site on a biomolecule. These conjugates are typically water soluble and have advantageous pharmacological properties (eg, reduced immunogenicity and increased circulation time). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013035763-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011521067-A |
priorityDate |
2004-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |