| abstract |
The present invention relates to novel substituted quinoline compounds and their pharmaceutically acceptable salts, esters or prodrugs. The invention further relates to a composition of the novel substituted quinoline compound in combination with a pharmaceutically acceptable carrier. The invention further relates to the use of the novel compounds as kinesin spindle protein inhibitors. The compounds of the present invention have the following general formula (I): Substituents and variables in general formula (I) are defined herein. |