abstract |
Provided are compounds of formula (I) having the meanings described by X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 , and pharmaceutically acceptable salts thereof. Thus, the compounds are useful in the treatment of diseases where inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and / or required, particularly in the treatment of inflammation. [Chemical 1] |