http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008501697-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2005-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2008501697-A |
| titleOfInvention | Methods of changing the CD4 / CD8 ratio and mononuclear cell infiltration into tumors |
| abstract | A method of altering the CD4 / CD8 ratio and mononuclear cell infiltration into a tumor resulting in a substantial change in infiltrating immune cells due to a decrease in CD8 + T cells and a substantial increase in tumor infiltrating CD4 + T cells. Leukocyte interleukin injection which is a serum-free and mitogen-free mixture containing the cytokines IL-1β, TNF-α, IFN-γ and GM-CSF and interleukin 2 (IL-2) at a specific ratio A paradigm shift occurred when agent (LI) was administered at a dose of 800 IU / day (converted to IL-2) 5 days a week for 3 weeks. This paradigm shift is a clear and specific distribution of CD4 + T cells and the density and local distribution of antigen presenting cells (eg, dendritic cells) and inflammatory cells (especially neutrophils) in the cancer nest Defined by change. [Selection figure] None |
| priorityDate | 2004-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 453.