| abstract |
The present invention relates to a pharmaceutical composition comprising irbesartan and provides an oral formulation comprising a high relative amount or concentration of irbesartan. In one embodiment, the present invention provides an oral formulation of irbesartan comprising greater than 70% w / w irbesartan. In another embodiment, the present invention provides that USP apparatus 2 uses about 30% greater than about 85% irbesartan when placed in 1000 mL 0.1 N hydrochloric acid at 37 ° C. at a paddle speed of 50 rpm. An oral formulation of irbesartan is provided that exhibits a dissolution profile that dissolves within minutes. The formulation can optionally include at least one additional active ingredient. |