| abstract |
Methods of using GALR2-specific agonists in the preparation of a medicament for the prevention or treatment of brain damage, brain injury or brain disease are provided. Brain damage or brain injury is an embolic stroke, thrombotic stroke, or hemorrhagic stroke; direct or indirect trauma or surgery to the brain or spinal cord; ischemic damage to the brain during cardiopulmonary bypass surgery or kidney dialysis Or embolic damage; reperfusion brain damage associated with myocardial infarction; brain disease; excessive alcohol consumption or chemical damage as a result of administration of chemotherapeutic drugs for cancer treatment; radiation damage; or results of bacterial or viral infection Caused by one of the following: The brain disease can be one of Alzheimer's disease, Parkinson's disease, multiple sclerosis, or mutant Creutzfeldt-Jakob disease. |