| abstract |
Useful as a high conductance calcium-sensitive K-channel opener useful for the treatment of diseases such as frequent urination and urinary incontinence: [Wherein, ring Q represents pyridine or pyrimidine. Ring A represents benzene or a heterocyclic ring. G represents ring B which may have a substituent R 3 , or amino which may be substituted with one or two substituents selected from alkyl, cycloalkyl and aralkyl. Ring B represents benzene, heterocycle, cycloalkane or cycloalkene. R 1 represents a group selected from the following formulae. R 2 and R 3 are the same or different and each represents cyano, nitro or the like. m and n are the same or different and each represents 0, 1 or 2. R 4 represents a hydrogen atom, halogen or the like. R 5 and R 6 are the same or different and each represents a hydrogen atom, an optionally substituted alkyl, or the like. ] Or a pharmaceutically acceptable salt thereof. |