| abstract |
The present invention relates to novel pyrazinylmethyl a compound of formula I - lactam derivative (wherein R 1 is then a group of the formula G 1 or G 2 represented, wherein R 1, R 3, R 6, R 13 X, a, n and m are as defined herein), pharmaceutically acceptable salts thereof, and serotonin I (5-HT 1 ) receptors, in particular 15 of 5-HT 1A It relates to a pharmaceutical composition comprising selective agonists, antagonists, inverse agonists and partial agonists of one or both of the receptor and 5-HT 1B receptor. The compounds of the present invention, depression, anxiety, useful in the treatment or prevention of obsessive-compulsive disorder (OCD) and 5-HT 1 agonist or antagonist is other disorders necessary. [Chemical 1] |