| abstract |
Disclosed are compounds, compositions and methods for treating degenerative diseases and degenerative disorders. See the following compounds. This compound has cytoprotective properties and belongs to the class of cyclopentanophenanthrene-related steroids, which have a derivatized estrogen-like structure and do not have significant feminizing activity and have cytoprotective activity. Giving, thereby avoiding undesirable side effects, for example, in the treatment of degenerative disorders or for use in tissue transplantation or when administered therapeutically for other diseases, disorders or conditions. Such degenerative disorders include neurodegenerative disorders, eye disorders, cardiovascular disorders, mitochondrial diseases, bone disorders, joint disorders, connective tissue disorders or cartilage disorders, or excitotoxic pathway activity. Disabilities associated with change. |