| abstract |
The present invention relates to a method for inhibiting tumor cell formation or tumor cell growth, and a method for inducing apoptosis in sperm, which comprises administering to a patient an antagonist that inhibits MAGE gene expression or MAGE protein function Preferably, the antagonist is an anti-MAGE antibody, an antisense molecule and a siRNA molecule, a molecule that forms a triple helix nucleic acid molecule with a MAGE-encoding polynucleotide, or a small molecule inhibitor that inhibits MAGE function. provide. The present invention also discloses a pharmaceutical composition containing the above-mentioned substances and a method for screening substances that inhibit MAGE protein function. |