http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008297269-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ab3e1d2b9a4794709fe79651849d76e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-30 |
| filingDate | 2007-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcee470f35f7c207ccb70ddad18f7dfc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a03708184ae0d0dd273cbc43df992e1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2789204558ddf8eb7ee54368c5d571e |
| publicationDate | 2008-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2008297269-A |
| titleOfInvention | Process for producing (R) -3-morpholine carboxylic acid |
| abstract | An object of the present invention is to provide an industrially suitable method for producing (R) -3-morpholinecarboxylic acid having high optical purity in a simple and inexpensive manner. Step C, that is, (1) Step A in which L-4-oxalidine is diazotized with a diazotizing agent in an acidic solvent, and the diazonium salt solution is adjusted to pH 7 with an alkali agent; (2) To the solution obtained in step A, 0.5 to 1.2 molar equivalents of sodium hydroxide, potassium hydroxide or barium hydroxide are added to L-4-oxalidine to carry out a cyclization reaction, (B) Step B for producing a 3-morpholinecarboxylic acid solution; (3) Step C, in which the pH of the crude (R) -3-morpholine carboxylic acid solution obtained in Step B is adjusted to 6.5 to 7.0 and then purified using an ion exchange resin; And (R) -3-morpholine carboxylic acid having a high optical purity with the structural requirements. [Selection figure] None |
| priorityDate | 2007-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.