abstract |
A method for increasing muscle weight is provided. A substantially purified growth differentiation factor (GDF) receptor containing a GDF-8 (myostatin) receptor and its functional peptide portion, a virtual representation of the functional peptide portion, and a myostatin signal in a cell A method for modulating the effects of myostatin on cells by contacting the cells with a substance that affects transmission, as well as an abnormal amount of muscle or adipose tissue in the subject by modulating myostatin signaling in the muscle cells or adipose tissue cells of the subject Of growth of muscle or adipose tissue in eukaryotes by improving the severity of a pathological condition characterized at least in part by development, development, or metabolic activity, and by administering to the organism a substance that affects myostatin signaling How to adjust. [Selection figure] None |