| abstract |
An object of the present invention is to provide a novel histamine release inhibitor or leukotriene release inhibitor, a pharmaceutical, a food or drink or a cosmetic containing the same. A pharmaceutical, food or drink or cosmetic comprising a histamine release inhibitor or leukotriene release inhibitor containing naringenin chalcone or a salt thereof as an active ingredient, and the above-mentioned drug. The histamine release inhibitor or leukotriene release inhibitor of the present invention is useful as a prophylactic / therapeutic agent and anti-inflammatory agent for various allergic diseases. In addition, the histamine release inhibitor or leukotriene release inhibitor of the present invention inhibits histamine release from mast cells in type I allergic reactions, and thus atopic dermatitis, allergic rhinitis, hay fever It is particularly useful for the prevention and treatment of allergic asthma. [Selection] Figure 4 |