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filingDate 2007-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2008266276-A
titleOfInvention Composition for repairing damaged skin
abstract A buffer solution is added to a preparation for external use of PVP-I including povidone iodine (hereinafter referred to as PVP-I) sugar for the purpose of adjusting pH. However, since it exists in the form of KI 3 due to the influence of sodium ions contained in the buffer solution and the addition of KI, it has different properties from the PVP-I prototype. In addition, although PVP-I is naturally releasable in an aqueous solution, if there is an object to be reacted, iodine is rapidly released, so that it may be fatal to cause cytotoxicity. And PVP-I sugar for pressure ulcer treatment is a water-soluble base material, and it is easy to dry a wound part, and there is a high possibility of delaying healing. Therefore, a buffer solution or the like is not used, and a water-in-oil type emulsion base material is used to avoid direct contact with skin cell tissue by PVP-I. For that purpose, sodium hyaluronate and gelatin or derivatives thereof used as moisturizers are used for the purpose of surface activity. And the external pressure can be relieved by using gelatin. Moreover, the method of adding sodium hydrogencarbonate (henceforth sodium bicarbonate) to an oil layer can be taken for adjustment of PH. In this case, PVP-I and baking soda in the aqueous layer do not fade, and a preparation faithful to the PVP-I prototype can be obtained. As described above, the skin irritation was improved chemically and physically. [Selection figure] None
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