| abstract |
To stabilize lyophilized bone morphogenetic protein (BMP) so that the BMP retains at least 60% of its biological activity upon rehydration and the surgeon can easily handle the rehydrated liquid product Provide a protein stabilizing formulation. BMP-stabilized formulations and compositions comprising mainly lyophilized compositions and trehalose as an excipient for their subsequent storage and restoration. Other excipients can also be included, including buffers and surfactants. [Selection] Figure 1 |