http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008228644-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82787c2fee17b0b0eb295d5af7d2325f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3636b248feedab8841feb20799a07ddc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cba4fb82b1bec63b4a5f1e108e18a5ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9568ab25d04ae70cb070d390a5d6e6b0 |
| publicationDate | 2008-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2008228644-A |
| titleOfInvention | Prediction method of adverse drug reaction based on gene expression information |
| abstract | A method for identifying a gene capable of predicting an adverse drug reaction and a method for predicting an adverse drug reaction of a drug are provided. Corresponding to the central position of the regression line in each range of less than 10 mg, less than 10 mg and less than 400 mg, and more than 400 mg, based on the correlation between the maximum daily dose of the drug and the maximum blood concentration The above-mentioned method wherein the maximum blood concentration value ± 10% is the optimal drug exposure concentration, and human-derived cells are used as test drugs in accordance with the maximum daily use range of the drug in humans. A method for predicting an adverse reaction of a test drug by exposing to a determined optimal drug exposure concentration, detecting a change in gene expression in a cell, and analyzing the data by a statistical method. The above method wherein the appropriate drug exposure concentration and gene are those determined by the above method. [Selection figure] None |
| priorityDate | 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 218.