| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad8b9bd3da7b08ada4c1fb578a933473 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
2007-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_539bd63388aeaf9a6f325a58428b1bcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04eec2a867b837a91a11ebc50288081e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_124370ade9f7c06932b487f2f7aec6d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d364ee8010ba3d1f2235ea4e1c9a034f |
| publicationDate |
2008-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2008220174-A |
| titleOfInvention |
Transformed cells and transgenic non-human animals that co-express mutant β-synuclein and α-synuclein |
| abstract |
Disclosed are a transformed cell and a transgenic non-human animal that serve as models for neurodegenerative diseases. Also provided are a method for producing the transgenic non-human animal, a screening method for therapeutic agents for neurodegenerative diseases, and a method for assaying side effects of therapeutic agents for neurodegenerative diseases. The transformed cell of the present invention is one into which a promoter that functions in a host cell, a mutant β-synuclein gene and an α-synuclein gene are introduced. The transgenic non-human animal of the present invention is one into which a promoter that functions in central nervous system cells, a mutant β-synuclein gene, and an α-synuclein gene are introduced. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016180725-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9657103-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015517463-A |
| priorityDate |
2007-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |