| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc10898deaadd5a1818f4e222280d872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a2f6c7c3bab26acebfc65758157f2c2 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-033
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2007-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9535a0ce4eaaf6b88d52f787badf8d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bdc5790f7a542d7dc5c8665285de78d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_651f84d829ea24436b54063672dbd675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8371513cd4a587206ccdec125c1e9bf2 |
| publicationDate |
2008-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2008187947-A |
| titleOfInvention |
Silkworms with high expression of useful proteins by antiviral protein gene knockdown and use thereof |
| abstract |
A method for mass production of useful proteins by a viral vector-silkworm expression system. In a baculovirus vector expression system, it was hypothesized that suppression of virus growth by antiviral activity of insects may lead to a decrease in high expression of expressed protein. A transgenic silkworm that knocks down AVP that exhibits antiviral activity is prepared, and a baculovirus (silkworm Bombyx mori NPV (BmNPV) or hybrid NPV (HyNPV)) that is commonly used as a vector for high protein expression in this silkworm is used as a vector. Useful proteins were expressed. The protein expression level in the AVP gene knockdown silkworm increased more than 3 times compared to the control silkworm. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8222479-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8519101-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8394942-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104561019-A |
| priorityDate |
2007-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |