abstract |
Provided is an aminoacylase gene suitable for producing optically active amine compounds and the like. Formula (1): (wherein R 1 represents an optionally substituted aryl group, R 2 represents a C1-3 alkyl group, and R 3 represents a C1-6 alkyl group. And the acylamide represented by * is stereoselectively hydrolyzed to give a compound of formula (2): (wherein R 1 , R 2 , R 3 , * Is a DNA comprising a base sequence encoding a protein having the ability to be converted into an optically active amine compound represented by the above). [Selection figure] None |