| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e5c121269689cbab9b3a4548b15caf3 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-52 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-549
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
| filingDate |
2006-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a2db151f90e8a112e3307b58a9fc6a7 |
| publicationDate |
2008-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2008143848-A |
| titleOfInvention |
Method for predicting diuretic sensitivity in hypertensive patients. |
| abstract |
Provided is a method for selecting and determining hypertensive patients in which the diuretic effectively responds based on gene polymorphisms related to the effectiveness of hypoglycemic agents containing diuretic as an active ingredient. In addition, a reagent and a reagent kit useful for simply carrying out the method are provided. An index is that a hypertensive patient has the following genotype for at least one gene of (1) to (4): (1) Glutamate-cystein ligase (C588T): genotype 1, (2) CD18 (C1323T): Genotype 23, (3) Cytochrome P450 2J2 * 7 (G-50T): Genotype 1, (4) Alcohol dehydrogenase 2 (Arg47His (G / A)): Genotype 1 . [Selection figure] None |
| priorityDate |
2006-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |