http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008134206-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_baee372c55802742f9582e25c15ff11a
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-26
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filingDate 2006-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dde7e19e1a94cc5e7bcf7b7d0a4fc95f
publicationDate 2008-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2008134206-A
titleOfInvention Mobile phase used in liquid chromatograph mass spectrometry, method for screening additive for the mobile phase, and liquid chromatograph mass spectrometric method
abstract To screen for carboxylic acids capable of realizing both analytical sensitivity and separation performance by adding an appropriate additive to a mobile phase. (A) a step of measuring a retention time and an electron spray ion (ESI) signal intensity of a cationic analyte when each of several carboxylic acids is added to a mobile phase; A step of constructing a first arithmetic expression having a physical property value as an explanatory variable and a second arithmetic expression having a retention time as an objective variable and a second arithmetic expression having an ESI signal intensity as an objective variable, respectively, and (c) a screening target A step of obtaining a physical property value of the carboxylic acid, and a step of (d) predicting the retention time and ESI signal intensity of the carboxylic acid to be screened by applying the physical property value obtained in step (c) to both arithmetic expressions. , (E) when the predicted retention time is compared with that when acetic acid is added as an additive, and when the predicted ESI signal intensity is added as an additive with trifluoroacetic acid Comparison. [Selection] Figure 1
priorityDate 2006-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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