| abstract |
PROBLEM TO BE SOLVED: To provide a protein or peptide comprising at least one epitope of cedar pollen allergen Cry j II, particularly a T cell epitope, useful for diagnosis, prevention and treatment of cedar pollinosis. The cDNA encoding the cedar pollen allergen Cry j II was cloned and the entire amino acid sequence of Cry j II was clarified. Furthermore, an overlapping peptide was synthesized over the entire length of the amino acid sequence, and an overlapping peptide containing a T cell epitope was identified using a Cry j II T cell line derived from a cedar pollinosis patient. [Selection] Figure 9 |