| abstract |
PROBLEM TO BE SOLVED: To provide a new family of immune receptor molecules of the immunoglobulin superfamily, leukocyte immunoglobulin-like receptor (LIR) polypeptide. Sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA hybridizing to oligonucleotide probes having defined sequences, for producing LIR family polypeptides Methods and antagonistic antibodies to LIR family members. LIR family members can be used for the treatment of autoimmune diseases and disease states associated with suppressed immune function. [Selection figure] None |