| abstract |
Disclosed is a novel compound useful for treating a specific metabolic disease through inhibition of malonyl-CoA decarboxylase (MCD). Compounds represented by formulas (I) and (II) Wherein Y is S or O; C is a substituted monocyclic 5- to 7-membered ring containing 1 to 3 heteroatoms, R1 and R2 are different, each independently hydrogen, A halogen, C1-C12 alkyl, etc., or a substituted or unsubstituted monocyclic 3-7 membered ring containing a heteroatom, R7 is selected from hydrogen, C1-C12 alkyl, halogen, etc., or R7 and R6 are Both may form a fused substituted 5- to 7-membered ring containing 1 to 3 heteroatoms selected from N, O, or S.) [Selection figure] None |